World's First Success in Visualization of Coenzyme Broadly Related to Vital Activities and Diseases

A Japanese research team led by Dr. Hirokazu Komatsu, a researcher at the International Center for Materials Nanoarchitectonics (MANA: Director: Masakazu Aono) of the National Institute for Materials Science (NIMS; President: Sukekatsu Ushioda) in charge of the YAMATO-MANA Program, and Dr. Katsuhiko Ariga, MANA Principal Investigator and Supermolecule Unit Leader, in collaboration with Project Professor Yutaka Shido and Professor Kotaro Oka of the Department of Biosciences and Informatics, Faculty of Science and Technology, Keio University (President: Atsushi Seike), succeeded for the first time in the world in developing an imaging method for visualization of nicotine-adenine dinucleotide derivative (NAD(P)H) in a cell, a coenzyme broadly related to vital activity and illness, which had previously been elusive.


Moffitt Cancer Center Begins Phase I Clinical Trial of New Immunotherapy

Moffitt Cancer Center has initiated a phase I clinical trial for a new immunotherapy drug, ID-G305, made by Immune Design. Immunotherapy is a treatment option that uses a person’s own immune system to fight cancer. It has several advantages over standard cancer therapies, including fewer side effects and an overall better tolerability. It tends to be most effective in patients who have smaller, localized tumors that have not spread to distant sites. 


Scientists Grow Cartilage to Reconstruct Nose

Scientists at the University of Basel report first ever successful nose reconstruction surgery using cartilage grown in the laboratory. Cartilage cells were extracted from the patient’s nasal septum, multiplied and expanded onto a collagen membrane. The so-called engineered cartilage was then shaped according to the defect and implanted. The results will be published in the current edition of the academic journal The Lancet.


Regular physical activity reduces breast cancer risk irrespective of age

Practising sport for more than an hour day reduces the risk of contracting breast cancer, and this applies to women of any age and any weight, and also unaffected by geographical location, according to research presented to the 9th European Breast Cancer Conference (EBCC 9).

Compared with the least active women, those with the highest level of physical activity reduced their risk of breast cancer by 12%, researchers say.


Ancient Chinese medicine put through its paces for pancreatic cancer

The bark of the Amur cork tree (Phellodendron amurense) has traveled a centuries-long road with the healing arts. Now it is being put through its paces by science in the fight against pancreatic cancer, with the potential to make inroads against several more.

UT Health Science Center researcher A. Pratap Kumar was already exploring the cork tree extract’s promise in treating prostate cancer when his team found that deadly pancreatic cancers share some similar development pathways with prostate tumors.


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