Approximately 12,000 spinal cord injuries (SCI) happen every year in the U.S., the majority caused by car accidents, falls, sporting accidents and gunshot wounds. Better emergency care and therapy have made SCI manageable, but researchers continue to investigate approaches to make it repairable. A new study in Journal of Neurophysiology reports that peripheral nerve stimulation therapy can reverse SCI-associated nerve deterioration, potentially improving the benefits of current and emerging rehabilitation treatments.
Cancer drug promotes regeneration of damaged neurons.
Bonn, March 12th, 2015. Damage to the spinal cord rarely heals because the injured nerve cells fail to regenerate. The regrowth of their long nerve fibers is hindered by scar tissue and molecular processes inside the nerves. An international team of researchers led by DZNE scientists in Bonn now reports inScience that help might be on the way from an unexpected quarter: in animal studies, the cancer drug epothilone reduced the formation of scar tissue in injuries to the spinal cord and stimulated growth in damaged nerve cells. Both promoted neuronal regeneration and improved the animals' motor skills. (suwe)